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报道了一种生产新霉素的新工艺.该工艺除去摇瓶发酵原培养基中的玉米浆、花生饼粉及玉米淀粉,添加促进剂甘氨酸、赖氨酸、酪氨酸、蛋氨酸,不改变原菌种遗传性状(DNA)36℃培养.摇瓶发酵周期由136 h缩短到112h,产素率(单位时间、单位体积产抗生素的量)提高30%以上,简化了生产工艺,降低了生产成本.
Abstract：A new technique to produce neomycin is created.It needs to remove the corn steep liquor,peanut cake powder,corn starch of the original medium,add the accelerators such as glycine,lysine,tyrosine,methionine,and incubate at 36℃ in shaking flask.The fermentation period of shaking flask shortens from 136 h to 112 h,and the rate of antibiotic production increases over 30%.It reduces the costs of production and simplifies the working process.
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基本信息:
中图分类号:TQ465
引用信息:
[1]管玉霞.增加新霉素产量的研究[J].郑州大学学报(理学版),2006(02):110-112.
2006-06-30
2006-06-30